The Human Brain:
The Structural Basis for Understanding Human Brain Function and Dysfunction

+++ INTERNATIONAL CONFERENCE +++ ROME +++ IRCCS SANTA LUCIA +++ Oct. 5-10, 2002 +++

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Margaret Martínez-de-la-Torre
Dept.Morphological Sciences, Univ.of Murcia, Spain
e-mail: margaret@um.es

Poster Presentation:
Cytoarchitectonic delineations in the foetal human brain at four months of gestation.
Margaret Martínez-de-la-Torre and Luis Puelles
Dept.Morphological Sciences, Medical School, University of Murcia, Murcia, Spain
A well-fixed and well conserved human foetus at 4 months' gestation served to dissect the brain and obtain serial coronal paraffin sections through it, subsequently stained with cresyl violet. The surface of the telencephalon is largely smooth, except for a distinct insular fossa and incipient hippocampal and paracallosal sulci at the interhemispheric aspect. Numerous cytoarchitectonic details can be distinguished: In the telencephalon, the primordia of isocortex and hippocampal and piriform allocortex, claustrum, amygdala, septum and basal ganglia. Notably, the medial ganglionic eminence appears distinct from the lateral partner by a more intense basophilia. The medially adjacent bed nucleus of the stria terminalis is distinctly paler, similar to the globus pallidus. A number of hypothalamic, thalamic, midbrain and hindbrain structures can be identified as well. Choroidal plexi and taeniae are well preserved. A possible remnant of a sauropsodian-like \"dorsal ventricular ridge\" is shown at rostral section levels, behind the olfactory bulb. This developmental stadium is thought to be useful for didactic purposes in medical studies, and is so employed in our school.

 

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